Weight gain

If the patient has developed central weight gain as well as thinned, reddened skin, acne, hirsuitism, muscle weakness, diabetes, hypertension, hypokalaemia or osteoporosis, consider Cushing’s syndrome.

If the weight gain is long standing, onset has been very gradual, and weight fluctuates with life events and dieting, consider simple obesity.

If they have developed menorrhagia, constipation or tiredness, consider hypothyroidism.

If the weight gain was gradual, started in puberty, and is associated with hirsuitism, acne and oligomenorrhoea consider polycystic ovarian syndrome.

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