If the patient describes general heat intolerance, with weight loss, anxiety, tremulousness, palpitations, diarrhoea or oligomenorrhoea, consider thyrotoxicosis.

If the patient describes a feeling of dry warmth, flushing of the face, diarrhoea or episodic wheeze, consider carcinoid syndrome.

If the patient actually complains of a generalised increase in sweating, and has soft tissue swelling, consider acromegaly.

If the flushes tend to be worse at night, and are associated with profuse sweating, consider any cause of hypogonadism, the commonest being premature ovarian failure.

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